Mechanisms of neuronal differentiation, development and function
The objective of this curricular unit is the acquisition of basic concepts of molecular neuroscience. Namely, to learn the molecular mechanisms involved in processes ranging from neuronal specification, to the development of mature functional neurons. Besides learning the syllabus, students should become familiar
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The main bibliography or other relevant learning resources will be provided by the various scientists that participate in the teaching activities. Whenever applicable bibliography should consist in scientific papers that are available in open access or in specific repositories accessible by the students. In each edition of the course the most updated and current bibliography will be provided. Students are encouraged to share notes and other relevant information concerning the UC in virtual fora or virtual blackboards.
Teaching will be based on a combination of research seminars, workshops, journal clubs, together with practical classes, whenever possible. Teaching will be centered on the students, with the objective of making them independent and capable to conceive and develop a project in the area of molecular neurobiology. Typically, the optional advanced courses will be based on a combination of seminars and more work performed by the student. The evaluation will be based on the discussion and presentation of the work done by the student, its participation in the curricular unit, and in a written test which will allow to level all students for the application of knowledge acquired during the courses to concrete situations related with molecular neuroscience.
Evaluation will be carried out during the unit based on general performance and participation (20%),
Students should acquire knowledge and concepts on the following topics of basic mechanisms of molecular neuroscience: Neuroblast to neuron specification; Neuronal migration and pathfinding; Synaptogenesis; Mechanisms of synaptic growth and maintenance; Neuronal communication; Synaptic plasticity; Glia in the nervous system; Neurodegeneratione neuroregeneration.
Programs where the course is taught: