Metabolic Integration and Nutrition


This UC is intended that students know in depth the metabolism of the main biomolecules of the human organism and to understand the metabolism of an integrated and global manner. The role of diet on disease should not only be focused on the epidemiological data but also on the evidence about disease mechanisms. It is intended that the student is able to know: (a) the integration of metabolism; (b) the mechanisms responsible for its regulation and the relationship with the disease; (c) the metabolism in the light of chronobiology; (d) role of diet in epigenetic regulation and (e) the role of diet in microbiota modulation and dysbiosis.

General characterization





Responsible teacher

Profª Doutora Conceição Calhau


Weekly - Available soon

Total - Available soon

Teaching language





·        Gropper S.S., Smith J.L., Groff J.L. Advanced Nutrition and Human Metabolism. 5th. ed. Wadsworth, Cengage Learning, 2009.

·        Frayn KN. Regulação metabólica. 3rd ed. U. Porto Editorial. Porto. 2012

Teaching method

The theoretical classes offer a detailed and complete exposition of the programmatic contents and broaden the critical spirit of the student in relation to the subjects presented. The final exam aims to evaluate all the knowledge acquired in the theoretical classes, which are very important basic knowledge for learning many topics that will be developed during the Masters in Human Nutrition and Metabolism.

Theoretical training provides the acquisition and theorical application of knowledge, development of skills and motivation necessary to fulfill the educational goals of the course. The evaluation of learning and teaching are implemented to enable the identification of strengths and weaknesses of the course as an important gauging tool with the aim of continuous improvement.

Evaluation method

Main lectures with exposure of the contents of the course. Presentation of cases and problem solving.


The evaluation will be made taking into account the following parameters: Clinical cases discussion/journal club (50%); Examination (50%).


Students with a grade equal to or greater than 10 (0 - 20) values in each of the evaluation elements, are approved.

Subject matter

1. Integration of Carbohydrate, Fat, and Protein Metabolism

2. Cellular Mechanisms Involved in Metabolic Regulation

3. The Nervous System and Metabolism

4. Chronobiology, metabolism and nutrition
Epigenetic regulation

5. Microbiota


Programs where the course is taught: