Research Design and Methods in Nutrition


The students in this UC make contact with scientific method and the various options of experimental models. For this purpose, students must be able to: (1) identify and decide, according to the problem in question, what is the best experimental model to use in a particular study; (2) To know and work with any of the models, knowing the lab technics, ethics rules, the advantages but also the limitations of each model; (3) recognize a good scientific communication; (4) understand the scientific methodology as a tool of professional practice; (5) understand the results in a scientific communication with the criticism needed.

General characterization





Responsible teacher

Profª Doutora Conceição Calhau


Weekly - Available soon

Total - Available soon

Teaching language





·        Julie A. Lovegrove (Editor), Leanne Hodson (Editor), Sangita Sharma (Editor), Susan A.

·        Lanham-New (Editor). (2015). Wiley-Blackwell Nutrition Research Methodologies

·        Publicações cientificas atuais

Teaching method

The learning objectives of the CU require a teaching methodology that respects regular proximity to work and progress of students, respect for diversity of approaches and consideration of the uniqueness of individual cases and bring them to the forefront of the learning-teaching process. These starting principles are rightly included in the methodology adopted.

Evaluation method

No módulo 1, os estudantes terão aulas de laboratório, quer para o contacto com o modelo animal, quer para a manipulação de linhas celulares.

Avaliação: A UC terá no final uma prova escrita que consiste na apresentação de problemas e o estudante deve apresentar propostas de resposta com desenho de estudos experimentais, fundamentando. Esta UC tem ainda uma componente de avaliação contínua que decorre ao longo das aulas TP. Nestas aulas o estudante é confrontado com a aplicação dos conhecimentos transmitidos ao longo das aulas T. Nestas aulas TP serão também apresentados artigos científicos para discussão.

Subject matter

Module 1
The scientific method in Nutritional Sciences.
Animal models applied to research in nutrition (Rat, Mouse, or other) - requirements, advantages and disadvantages of these models. Animal models commonly used for various metabolic diseases: knockout animals, transgenic, obesity-diet induced/diabetes-diet induced, among others.
Cellular models in nutritional research.
Translation of nutritional research

Module 2
Presentation and discussion of LIC (Clinical Research Law): clinical studies of nutrition.
European regulations for nutritional and health claims.
Clinical studies in nutrition: leges artis. Special features of experimental design (intervention studies and observational studies).

Module 3
Ethical and deontological problems in these studies.
Trial registration. Documents required for the approval by the Ethics Committee.
Clinical studies and National Data Protection Commission.

Module 4
Scientific writing.
The dissemination of science.
The exercise of the profession based on the evidence.


Programs where the course is taught: