Membranes in Downstream Processing
Objectives
- To acquire general concepts about downstream processing
- To be able to apply previous knowledge, acquired in separation processes and transport phenomena, in the processing of biological media
- To be able to design process integration schemes
- To acquire knowledge about emerging process monitoring tools and their use for process control
- Understand how a specific problem may be approached by the Industry
General characterization
Code
10191
Credits
6.0
Responsible teacher
Isabel Maria Rola Coelhoso, João Paulo Serejo Goulão Crespo
Hours
Weekly - 4
Total - 57
Teaching language
Português
Prerequisites
Available soon
Bibliography
- Monitoring and visualizing membrane based processes. Edited by Carme Güell, Montserrat Ferrando, Francisco López. 2009 Wiley-VCH Verlag GmbH & Co. KGaA Weinheim;
- Microfiltration and Ultrafiltration: Principles and applications. Leos J. Zeman and Andrew L. Zydney, 1996 Marcel Dekker, Inc., New York;
- A. Fersht, Structure and Mechanism in Protein Science,W.H. Freeman and Company, New York, 1999.
- B. Valeur, Molecular Fluorescence. Principles and Applications, Wiley/ VCH, Germany, 2002.
- Marcel Mulder, Basic Principles of Membrane Technology, Kluwer Academic Press, 1996.
- E.L. Cussler, Diffusion, second ed., Cambridge University Press, Cambridge, 1997;
Teaching method
Available soon
Evaluation method
The evaluation includes:
- Scientific research project and corresponding report and discussion – individual
- Engineering project with report and oral presentation and discussion - group of 3 students.
- Tests (2) - individual
The final grade is composed by 25% of the grade obtained in the research project +25% of the grade obtained in the engineering project +50% of the grade obtained in the tests (average value of the two tests).
In each component of the evaluation the grade has to be >=9.5, in a scale 0-20.
Subject matter
- Introduction and general concepts
- Specificity of biological complex media and media /membrane interactions
- Product recovery and fractionation
- Product purification and polishing
- Hybrid processes and process integration
- Process monitoring and control