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Biomaterials

Objectives

To acquire deep knowledge in the area of biomaterials with detailed understanding of the composition and properties of the major classes of biomaterial used in medical devices, manufacture process and applications, interactions with implanted biomaterials, and issues associated with the use of surface modification methods to enhance the biocompatibility of materials. Regulatory and standards associated with quality will be included.

General characterization

Code

5340

Credits

6.0

Responsible teacher

João Paulo Miranda Ribeiro Borges

Hours

Weekly - 5

Total - 84

Teaching language

Português

Prerequisites

Available soon

Bibliography

  • Buddy D. Ratner et. al (ed), Biomaterials Science - An introduction to Materials in Medicine, Academic Press, New York, 2013 (3ª Ed.)
  • Rolando Barbucci (Ed.), Integrated Biomaterials Science, Kluwer Academic Pub., New York, 2002.
  • Teacher''''''''''''''''''''''''''''''''s handouts
  • Scientific articles of significant relevance 

Teaching method

The lectures will be supported by powerpoint slides. The objectives of each lesson and reading support are explained on the slides.

The practical classes will be conducted in the laboratory, where students perform exploratory experimental activities of the topics covered in the lectures.

Evaluation method

Basically, the evaluation shall take into account a theoretical component (35 %) and a practical component (65%), distributed by 5 elements of assessment:

  • 2 theoretical mini-tests (35%);
  • Evaluation of lab activities will be done by:
    • 1 Quiz-test on practical activities L1 to L3 (15 %)
    • A project work report, presented in article format (35 %);
    • Evaluation of Lab class development (5 %):
    • Oral presentation of the results of project (10 %).

Presence to all lab classes and its evaluation are mandatory for students to be approved in the course. Final grade will be obtained by the weighted average of all the above cited elements. Approval in the course also requires a minimum grade of 9.5 in the average of the grades of the 2 theoretical mini-tests.

Students will be excluded from the course if one of the above conditions is not satisfied.

Subject matter

Lectures

1. Introduction: Economical, Ethic and Social issues in Biomaterials Science
2. Synthetic biomaterials: structure-property relashionships
3. Protein-biomaterial interactions
4. Blood-biomaterial interactions. 
5. Immune response to biomaterials
6. Wound healing process
7. Biomimetic and intelligent materials
8. Biocompatibility evaluation

Lab classes

L1 - Synthesis of hydroxyapatite powders
L2- Drug Delivery from nanofibres 

L3 - Synthesis of magnetite nanoparticles and thermal characterization for hyperthermia applications