The learning outcomes of the Curricular Unit of Immunology in the course of Nutritional Sciences are that the students:
• Acquire knowledge about terminology and general concepts of Immunology
• Understand the constitution of the Immune System (IS) and the normal mechanisms of Immune Response (IR) as a defense mechanism
• know the pathology-inducing immune mechanisms and how the IR may be modulated
• Recognize the relationship between nutritional status and IS, and know how to identify the nutrients with a specific role in IS
• Recognize the food allergy mechanisms and know how to guide the diet of an allergic patient
• know how to relate the role of nutrition in autoimmune, oncological, cardiovascular and respiratory diseases
• The theoretical course will be accompanied by practical classes with practical demonstrations of the most important laboratory technology, as well as discussion of clinical cases with applicability in the clinical nutritionist practice

General characterization





Responsible teacher

Prof. Doutor Luís Miguel Borrego


Weekly - Available soon

Total - Available soon

Teaching language





• Abbas, A., Lichtman, A.H., Pillai, S. (2018) 9th ed. Cellular and Molecular Immunology. Elsevier.
ISBN 9780323479783.
• Arosa, F., Caetano, E., Pacheco, F. (2012) 2a ed. Fundamentos de Imunologia. Lidel.
ISBN 978-972-757-856-6.
• Punt, J., Stranford, S., Jones, P., Owen, J. (2019) 8th ed. Kuby Immunology W.H. Freeman and Company.
ISBN 9781464189784.
• Murphy, K., Weaver, C. (2017) 9th ed. Janeway's Immunobiology. Garland Science.
ISBN 978-0-815-34505-3

Teaching method

• 14 weeks of lectures (2h/week, taught with computer support methods) and theoretical-practical classes (2x1,5h/week, taught with audiovisual media, exemplification and execution of laboratory techniques).
• Distribution of students by 5 classes (minimum ratio: 1 teacher/15 students).
• Handhouts and scientific articles available at the Moodle platform.

Evaluation method

• UC assessment includes theoretical component and continuous assessment in theoretical-practical classes (ATP).
• Final UC evaluation (ACC): written test (1st season) or oral examination (2nd and special season). Written test: multiple-choice test with 80 questions (five options per question, only one correct), each corresponding to 0.25 values. Duration: 90 minutes.
Consultation of tests: by prior registration in time to be scheduled by the regent of the UC.
UC Final classification = (0.20*ATP) + (0.80*ACC)
Approval: minimum classification of 10 values.

Subject matter

• SI: Constitution and operation
• Innate and Adaptive Immune Response
• Complement System
• Complement and disease
• Maturation of T and B cells
• Antibodies and Antigens
• MHC and mechanisms of antigen presentation
• Immune Response Mediated by T and B cells
• Immune Tolerance and Regulation Mechanisms
• Hypersensitivity reactions
• Primary Immunodeficiencies
• Allergy and Hypersensitivity
• Autoimmunity
• Food allergy
• Immunity and Nutrition
• Immunopathology Diabetes
• Inflammation and Cancer
• Inflammation in Cardiovascular Disease and Respiratory
• Nutrition and Immunity
• Allergy and Cross Reactivity: Clinical Cases
• Allergy and Food Intolerance
• Nutrition and: Gastrointestinal Disease; Microbiota; Immunosuppression; Immunosuppression in Exercise;
• Immunomodulation in Diabetes, in Cardiovascular Disease, Obesity and respiratory disease, in Respiratory disease (asthma, COPD, sleep apnea); Cancer: Immune mechanisms
• Immune Response Evaluation in clinical practice: clinical and laboratory integration


Programs where the course is taught: