Immunology
Objectives
The learning outcomes of the Curricular Unit of Immunology in the course of Nutritional Sciences are that the students:
Acquire knowledge about terminology and general concepts of Immunology
Understand the constitution of the Immune System (IS) and the normal mechanisms of Immune Response (IR) as a defense mechanism
know the pathology-inducing immune mechanisms and how the IR may be modulated
Recognize the relationship between nutritional status and IS, and know how to identify the nutrients with a specific role in IS
Recognize the food allergy mechanisms and know how to guide the diet of an allergic patient
know how to relate the role of nutrition in autoimmune, oncological, cardiovascular and respiratory diseases
The theoretical course will be accompanied by practical classes with practical demonstrations of the most important laboratory technology, as well as discussion of clinical cases with applicability in the clinical nutritionist practice
General characterization
Code
41012
Credits
4
Responsible teacher
Prof. Doutor Luís Miguel Borrego
Hours
Weekly - Available soon
Total - Available soon
Teaching language
Portuguese
Prerequisites
Bibliography
Abbas, A., Lichtman, A.H., Pillai, S. (2018) 9th ed. Cellular and Molecular Immunology. Elsevier.
ISBN 9780323479783.
Arosa, F., Caetano, E., Pacheco, F. (2012) 2a ed. Fundamentos de Imunologia. Lidel.
ISBN 978-972-757-856-6.
Punt, J., Stranford, S., Jones, P., Owen, J. (2019) 8th ed. Kuby Immunology W.H. Freeman and Company.
ISBN 9781464189784.
Murphy, K., Weaver, C. (2017) 9th ed. Janeway's Immunobiology. Garland Science.
ISBN 978-0-815-34505-3
Teaching method
14 weeks of lectures (2h/week, taught with computer support methods) and theoretical-practical classes (2x1,5h/week, taught with audiovisual media, exemplification and execution of laboratory techniques).
Distribution of students by 5 classes (minimum ratio: 1 teacher/15 students).
Handhouts and scientific articles available at the Moodle platform.
Evaluation method
UC assessment includes theoretical component and continuous assessment in theoretical-practical classes (ATP).
Final UC evaluation (ACC): written test (1st season) or oral examination (2nd and special season). Written test: multiple-choice test with 80 questions (five options per question, only one correct), each corresponding to 0.25 values. Duration: 90 minutes.
Consultation of tests: by prior registration in time to be scheduled by the regent of the UC.
UC Final classification = (0.20*ATP) + (0.80*ACC)
Approval: minimum classification of 10 values.
Subject matter
SI: Constitution and operation
Innate and Adaptive Immune Response
Complement System
Complement and disease
Maturation of T and B cells
Antibodies and Antigens
MHC and mechanisms of antigen presentation
Immune Response Mediated by T and B cells
Immune Tolerance and Regulation Mechanisms
Hypersensitivity reactions
Primary Immunodeficiencies
Allergy and Hypersensitivity
Autoimmunity
Food allergy
Immunity and Nutrition
Immunopathology Diabetes
Inflammation and Cancer
Inflammation in Cardiovascular Disease and Respiratory
Nutrition and Immunity
Allergy and Cross Reactivity: Clinical Cases
Allergy and Food Intolerance
Nutrition and: Gastrointestinal Disease; Microbiota; Immunosuppression; Immunosuppression in Exercise;
Immunomodulation in Diabetes, in Cardiovascular Disease, Obesity and respiratory disease, in Respiratory disease (asthma, COPD, sleep apnea); Cancer: Immune mechanisms
Immune Response Evaluation in clinical practice: clinical and laboratory integration