The study of normal function of tissues and organs in the human body. One aims at the essential functional aspects of tissues and organs in order to understand underlying mechanisms in pathology, mechanisms of action of drugs and therapeutics. The course establishes a relationship between the concepts and respective application and promotes the use of reasoning to explain mechanisms and functional integration.

General characterization





Responsible teacher

Prof. Doutor Carlos Filipe


Weekly - Available soon

Total - Available soon

Teaching language





Costanzo, Linda S. - Physiology
Guyton, Arthur C. - Textbook of Medical Physiology


Ganong, William F. - Review of Medical Physiology

Berne, Robert M. and Levy, Mathew N. - Principles of Physiology Levick, J.R. - An Introduction to Cardiovascular Physiology Levitzky, M.G. - Pulmonary Physiology

Teaching method

Lectures (3 per week) and practical (two sessions of two hours per week) using numerical simulators of excitability, cardiovascular and respiratory system, kidney and hormones. The practical sessions include guidance and discussion by tutors.

Evaluation method

Throughout the semester the student can accumulate a maximum of 25% of the final score. For that, during the semester five tests are carried out focusing on the contents of the practical classes (scoring 5% each). The final exam (multiple choice test) is scored for 75%. The final result (sum of final exam score with the practical test scores) is converted to scale 0-20. To be approved the student has to add, in the set of practices and final examination ratings, a minimum of 48 percentage points (equivalent to 9.5 on the scale of 0-20). Regardless of the final classification, to be approved in the Curricular Unit of Physiology, students must have passed the final exam (number of questions in the final exam equal or greater than 36).

Subject matter

• Biophysics of excitability
• Synaptic transmission
• Mechanisms underlying muscle contraction
• Autonomic Nervous System
• Functional aspects of the cardiovascular system
• Regulatory aspects in the cardiovascular system
• Physical aspects underlying the exchange of gases in the lung
• Mechanical determinants of ventilation
• Physiology of Exercise and Thermoregulation
• Mechanisms underlying respiratory regulation
• Renal function
• Hormones and mechanisms underlying the function of the reproductive organs
• Physiology of sleep and circadian rhythms


Programs where the course is taught: