To acquire deep knowledge in the area of biomaterials with detailed understanding of the composition and properties of the major classes of biomaterial used in medical devices, manufacture process and applications, interactions with implanted biomaterials, and issues associated with the use of surface modification methods to enhance the biocompatibility of materials. Regulatory and standards associated with quality will be included.
João Paulo Miranda Ribeiro Borges
Weekly - 5
Total - 84
- Buddy D. Ratner et. al (ed), Biomaterials Science - An introduction to Materials in Medicine, Academic Press, New York, 2013 (3ª Ed.)
- Rolando Barbucci (Ed.), Integrated Biomaterials Science, Kluwer Academic Pub., New York, 2002.
- Teacher''s handouts
- Scientific articles of significant relevance
The lectures will be supported by powerpoint slides. The objectives of each lesson and reading support are explained on the slides.
The practical classes will be conducted in the laboratory, where students perform exploratory experimental activities of the topics covered in the lectures.
The evaluation shall take into account a theoretical component (55 %), a practical component (40%) and an overall performance assessment (5 %), distributed by 5 elements of assessment:
- Evaluation of the theoretical component (individual) will take into account:
- A critical/perspective essay related to Biomaterials (30 %) (due date = 20th November 2020);
- 1 mini-test (25 %) - 22nd December 2020
- Evaluation of lab activities (in group) will be done by:
- Quiz-tests on practical activities L1 to L3 (average = 30 %)
- Oral presentation of the results of one of the labs L1 to L3 (10 %).
- Evaluation of course class development (attendance; autonomy; participation):
Essay as well as the presence to all lab classes and its evaluation are mandatory for students to be approved in the course. Final grade will be obtained by the weighted average of all the above cited elements. Students will be excluded from the course if one of the above conditions is not satisfied.
1. Introduction: Economical, Ethic and Social issues in Biomaterials Science
2. Synthetic biomaterials: structure-property relashionships
3. Protein-biomaterial interactions
4. Blood-biomaterial interactions.
5. Immune response to biomaterials
6. Wound healing process
7. Biomimetic and intelligent materials
8. Biocompatibility evaluation
L1 - Synthesis of hydroxyapatite or mesoporous bioglass powders
L2- Drug Delivery from hydrogels
L3 - Synthesis of magnetite nanoparticles and thermal characterization for hyperthermia applications
Programs where the course is taught:
- Biomedical Engineering
- Materials Engineering
- Micro and Nanotechnology Engineering
- Specialty Materials Science
- Specialty Biochemical Engineering
- Specialty Materials Engineering
- Specialty Chemical Engineering
- Molecular Genetics and Biomedicine
- Nanotechnologies and Nanosciences
- Food Technology and Safety