Applied Organic Synthesis



This  course  deals  with  laboratory  techniques  in  organic  chemistry  laboratory.  This course provides knowledge and experience in an organic chemistry laboratory, which allow students to plan a synthetic route for the preparation of organic compounds. The students must acquire experience in planning an experiment (preparation/purification of reagents and solvents, choice of reaction conditions), monitoring and isolation of the desired compounds. The aim is that student acquire skills of interpretation and critical analysis of the results obtained, planning a chemical reaction and bibliographic search. Upon  successful  completion  of  this  course  students will posess practical skills required for work in modern chemical laboratory. 

General characterization





Responsible teacher

Maria Manuel Martinho Sequeira Barata Marques


Weekly - 1

Total - 28

Teaching language



Available soon


1. J. C. Gilbert, S. F. Martin, “Experimental Organic Chemistry. A Miniscale and Microscale Approach”, Thomson 2006
2. A. I. Vogel, A. R. Tatchell, B. S. Furnis, A. J. Hannaford , P. W. G. Smith “Vogel’s Textbook of practical organic chemistry”,
Prentice Hall 1996
3. J. W. Zubrick “The Organic Chem Lab Survival Manual”, Wiley 2010
4. L. M. Harwood, C. J. Moody, J. M. Percy “Experimental Organic Chemistry, Standard and Microscale”, 2 nd ed., Blackwell Science 1999
5. P. G. M. Wuts, T. W. Greene “Greene’s Protective Groups in Organic Synthesis”, any edition, Wiley & Sons
6. W. L. G. Armarego, C. L. L. Chai, “Purification of Laboratory Chemicals” any edition, Elsevier
7. C. F. Wilcox, Experimental Organic Chemistry, A Small-Scale Approach”, MacMillan Publishing Company, New York 1988

Teaching method

Pratical course of research-oriented experiments, involving techniques  employed  in  synthetic organic chemistry.

Evaluation method

This discipline contains the following evaluation items:

- 35% - previous presentation of the research plan - evaluation seminar-type;

- 30% - experimental work - laboratory performance;

- 25% - final report;

- 10% - Lab journal.

Subject matter

The  aim  is  to  provide  the students with  experience  with  techniques  employed  in  synthetic organic chemistry and to introduce the exciting research area of asymmetric organic synthesis.  The program includes a short synthetic sequence, involving different chemical transformations and a final application of the product prepared. This is a research-inspired experiment based on a useful class of chiral catalysts.


Programs where the course is taught: