Processos em Engenharia com Solventes Alternativos


1.   Acquire knowledge on alternative solvents, their properties, phase diagrams with other relevant compounds and uses.
2.   Recognize important properties of solvents and how to manipulate their chemical structure in order to obtain desired chemical properties.
3.   Integrate and interpret the different roles of one solvent in different parts of the same process.
4.   Use appropriate software to predict relevant process properties of solvents and interpret the results.
5.   Identify, in a scientific way, the underlying physical phenomena to the problem in question.
6.   Re-formulate scientific solvency problems taking into account process efficiency and economics as well as other environmental and human health issues.
7.   Develop critical thinking, question asking, problem solving and decision making in the context of solvent selection.
8.   Perform critical reading and assessing the literature for greenness and sustainability.9. Students will participate in discussion exercises and perform critical green audit of papers recently published in leading journals as well as current technological advances in the field.

General characterization





Responsible teacher

Ana Isabel Nobre Martins Aguiar de Oliveira Ricardo


Weekly - Available soon

Total - 72

Teaching language



Available soon


J.H. Clark, G.A. Kraus, A. Stankiewicz, P. Siedl, Y. Kou, Alternative Solvents for Green Chemistry, RSC Publications, 2nd Edition, 2012.

Innovations in Green Chemistry and Green Engineering; P. T. Anastas and J. B. Zimmerman Ed., Springer, New York, 2013.

Teaching method

Theoretical classes of exposition with 2h duration, including problem solving. Practical laboratory classes with 3 h duration that include the laboratory implementation and a written report.

Evaluation method

Evaluation: Reports and discussion on the practical sessions (25% of the final grade); Papers presentation and discussion (10% of the final grade); Case studies solving of selected themes (45% of the final grade) and oral presentation (20% of the final grade).

Subject matter

1- Alternative solvents and sustainable development (8 h).

Safety considerations: environmental, health; and safety properties; Life cycle assessment; Solvents in pharmaceutical industry. Solvent properties, polarity and solubility. Alternative solvents and alternative techniques in synthesis and processing. Solvent free chemistry.

2 - Supercritical solvents: properties and fundamentals. Supercritical carbon dioxide in synthesis, processing, separation and drying. Subcritical water. Case studies. (8 h).

3 – Room temperature ionic liquids, deep eutectic solvents. Properties and fundamentals. Applications of these solvents in synthesis, catalysis and extraction (6 h).

4 – (Bio)catalysis in non-aqueous media. Process design. Case studies. Industrial examples (6 h).



Programs where the course is taught: