Research in Leishmaniasis: Analysis and Applied Methodologies
After this unit, students should be able to:
1. To be able to apply the knowledge to select and carry out the main laboratory methodologies used for the diagnosis of leishmaniasis, including the ones for molecular species identification.
2. To have the ability to integrate knowledge and skilful with a reflection on the potential impact of climate and environmental changes on phlebotomine sand flies and on vector transmission of trypanosomatids, namely the genus
Weekly - Se a UC for oferecida como opcional, o horário será disponibilizado no 2º semestre
Total - 34
Attendance of 2/3 of classes is mandatory
• Schönian et al. (2003) PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagn. Microbiol. Infect. Dis. 47, 349–358. • Van der Auwera G et al. (2016). Comparison of Leishmania typing results in 16 European clinical laboratories. Eurosurveillance, 21(49): pii=30418. • Fischer, D., Thomas, S. M., Beierkuhnlein C. (2010). Temperature derived potential for the establishment of phlebotomine sandflies and visceral leishmaniasis in Germany. Geospatial Health, 5, 5969. • Barrett MP (2018) The elimination of human African trypanosomiasis is in sight: Report from the third WHO stakeholders meeting on elimination of gambiense human African trypanosomiasis. PLoS Negl Trop Dis 12(12): e0006925. • Hau, J., and Schapiro, S. J. (2010). Handbook of laboratory animal science. Essential principles and practices. London: CRC Press.
The methodology used in classes is essentially expository, based on the use of PowerPoint slide presentations and posters. Most teaching hours are practical or theoretical-practical with the execution of techniques, problem solving, analysis and discussion. In practical sessions theoretical knowledge will be applied. Students in groups of 2-3 each will draw and will prepare a PowerPoint slide presentation regarding a proposal for a research project on the themes addressed in UC, followed by discussion of the subject, objectives, material and methods and waiting results.
The final evaluation of the UC is composed of: active participation in practical classes (20%) and evaluation given to the research project (80%). To obtain approval in the UC, attendance in at least 2/3 of the classes is mandatory, and a final average ≥ 10.
I. Climate change on vector-borne transmission of
Programs where the course is taught: