Biostatistics II


After this unit, students should be able to:
1. Identify characteristics of a problem to use the appropriate multivariate statistical methods.
2. Check and respect the conditions of applicability of these techniques.
3. Understand data limitations and verify the assumptions of statistical techniques.
4. Perform the most appropriate analysis using a statistical package (e.g SPSS) and extract the pertinent or relevant information from the output provided by the software.
5. Improve critical interpretation of statistical analysis of data in medical research.

General characterization





Responsible teacher

Luzia Gonçalves


Weekly - Se a UC for oferecida como opcional, o horário será disponibilizado no 2º semestre

Total - 24

Teaching language



Not applicable


• Branco, J.A. (2004) Uma Introdução à Análise de Clusters. Sociedade Portuguesa de Estatística.
• Hosmer, D.W., Lemeshow, S. (1991) Applied Logistic Regression. John Wiley and Sons. 2ª Edição.
• Hair, J.F., Anderson, R.E., Tatham, R.L., Black, W. C. (2005) Análise Multivariada de Dados. Bookmam. 5ª Edição.
• Harrell, F. E. (2001) Regression Modeling Strategies with Applications to Linear Models, Logistic Regression, and Survival Analysis. Springer.
• Maroco, J. (2014) Análise estatística com o SPSS. Edições Silabo. 6ª Edição.

Teaching method

Theoretical and practical classes, reinforced by e-learning platform of IHMT and other internet resources. Practical classes and tutorials include dataset analysis, using SPSS program or similar package. Videos and written information will be provide, as well articles for discussion.

Evaluation method

The final assessment will be combined a written exam (60%) and an individual written work (40%). The exam includes different type of questions (e.g. multiple choice, true/false and essay questions). The written work is the result of the statistical analysis of a database, using a statistical package.

Subject matter

I. Assumptions and interpretation of parameters, assessment of model fit and validation of the fitted models. Practical considerations in international health.
II. Multiple linear regression: model assumptions, interpretation of parameters and validating the fitted model.
III. Multiple logistic regression: model assumptions, interpretation of parameters and validating the fitted model.
IV. Multidimensional contingency tables: Chi-Square test and log-linear analysis.
V. Cluster Analysis and Factorial Analysis.
VI. Applications using SPSS Program: assumptions, model fitting, variable selection, diagnostic tools and model validation.