Leptospirosis and Lyme Borreliosis: Reemerging Diseases in the Global World
Objectives
- Understand the (re)emerging epidemiological importance from the two zoonotic spirochetoses, with a particular focus on the situation in Portugal, namely on Azores Archipelago;
- Know and apply the current laboratory approaches (immunological and molecular) in order to improve laboratory diagnosis;
- Interpret the laboratorial results versus the biology and pathogenesis of the involved agents (leptospires and borreliae) and their impacts on human population.
General characterization
Code
12368
Credits
6.0
Responsible teacher
Maria Luísa Jorge Vieira
Hours
Weekly - 3
Total - 44
Teaching language
Português
Prerequisites
Available soon
Bibliography
The students have access to the slides (PPT) of the classes, and to the links of videos, through an available platform (Moodle); to the Laboratory Manual prepared and updated in each edition of the Master, with the protocols and theoretical basis of each technique, to the bibliography, which will be complemented with other current bibliographic elements, during the Course.
(Books and review articles recommended by teachers)
Teaching method
Lectures (L), theoretical-practical (TP), practical laboratory (PL) and tutorial classes.
Evaluation method
Students at least 2/3 attendance: continuous assessment [class attendance and active participation (in particular in practical components), discussion performance (round table)]: 30%
Oral presentations (seminar): 20%;
Final written exam (multiple choice + open questions): 50%;
Approval rated ≥ 10 (0-20 scale).
Subject matter
|
CURRICULAR UNIT |
DATES |
SCHEDULE |
SYLLABUS |
|
Leptospirose e Borreliose de Lyme: Doenças Reemergentes no Mundo Global / |
18/05/2020 |
16 - 17 horas (TO) |
Curricular Unit Presentation: schedule and distribution of documentation (TO) - Maria Luisa Vieira |
|
18/05/2020 |
17 - 19 horas (L) |
Leptospires and Leptospirosis: theme update (L) - MLVieira |
|
|
18/05/2020 |
19 - 20 horas (PL) |
Microscopic observation of leptospires (dark field mic.) (PL) - Teresa Carreira e MLVieira |
|
|
19/05/2020 |
16 - 17 horas (TP) |
Leptospirosis and the laboratory (TP) - MLVieira |
|
|
19/05/2020 |
17 - 20 horas (PL) |
Laboratory diagnosis tests [MACROLepto and MAT (WHO reference test)] (PL) - TCarreira e MLVieira |
|
|
|
20/05/2020 |
16 - 20 horas (PL) |
Laboratory (continuation) Molecular tests in the diagnosis of human leptospirosis (conventional PCR and nested-PCR) (PL) - TCarreira e MLVieira |
|
|
21/05/2020 |
16 - 20 horas (PL) |
Molecular detection of Leptospira spp in environmental samples (real-time PCR) (PL) - Maria Fernandes; TCarreira e MLVieira |
|
|
25/05/2020 |
16 - 18 horas (L) |
Ixodids as vectors of Borrelia spp (L) - Paulo Almeida
|
|
|
25/05/2020 |
18 - 20 horas (PL) |
Observation / identification of ixodids with importance in transmission of Borrelia burgdorferi s.l. spirochetes complex (PL) - Teresa Novo e PAlmeida |
|
Leptospirosis and Lyme Borreliosis: Reemerging Diseases in the Global World |
26/05/2020 |
16 - 18 horas (T) |
Importance of Rodents in the Epidemiology of Leptospirosis and in the zoonotic cycle of Lyme Borreliosis agents (T) - MLVieira |
|
|
26/05/2020 |
18 - 20 horas (TP) |
Spirochetes and research - current challenges (TP) – Invited Lecturer and 2 former students of previous MMM edition TCarreira e MLVieira |
|
|
27/05/2020 |
16 - 18 horas (T) |
Borreliae and Lyme Borreliosis: theme update (T) - MLVieira |
|
|
27/05/2020 |
18 - 19 horas (TP) |
Lyme Borreliosis and the Laboratory (TP) - MLVieira |
|
|
27/05/2020 |
19 - 20 horas (PL) |
Microscopic observation of borreliae maintained in BSK selective medium (PL) - TCarreira e MLVieira |
|
|
28/05/2020 |
16 - 20 horas (PL) |
Laboratory Diagnosis (IFA and Western Blot tests) (PL) - TCarreira e MLVieira |
|
|
01/06/2018 |
16 - 20 horas (PL) |
Borrelia burgdorferi s.l. complex and other borreliae/ (PL) - Invited Lecturer, TCarreira e MLVieira |
|
|
02/06/2018 |
16 - 18 horas (L) |
Leptospirosis and Lyme Borreliosis - clinical perspective (L) - Jorge Seixas |
|
|
02/06/2018 |
18 - 20 horas (TP) |
Roundtable - Discussion of Results / oral presentations (lab protocols previously distributed) (TP) - TCarreira, MFernandes, MLVieira and other teachers involved in Curricular Unit |
|
|
03/06/2020 |
16 - 20 horas (TO) |
Reviews and answering questions (TO) – MLVieira (4h) ; TCarreira (2h) |
|
|
04/06/2018 |
16 - 18 horas (E) |
Assessment of knowledge - Written test (E) - MLVieira |
|
|
04/06/2018 |
18,30 - 19 h |
Evaluation survey of teaching and teachers (if on paper) |