Metabolic Integration and Nutrition


This UC is intended that students know in depth the metabolism of the main biomolecules of the human organism and to understand the metabolism of an integrated and global manner. The role of diet on disease should not only be focused on the epidemiological data but also on the evidence about disease mechanisms. It is intended that the student is able to know: (a) the integration of metabolism; (b) the mechanisms responsible for its regulation and the relationship with the disease; (c) the metabolism in the light of chronobiology; (d) role of diet in epigenetic regulation and (e) the role of diet in microbiota modulation and dysbiosis.

General characterization





Responsible teacher

Professora Doutora Conceição Calhau


Weekly - Available soon

Total - Available soon

Teaching language





·        Gropper S.S., Smith J.L., Groff J.L. Advanced Nutrition and Human Metabolism. 5th. ed. Wadsworth, Cengage Learning, 2009.

·        Frayn KN. Regulação metabólica. 3rd ed. U. Porto Editorial. Porto. 2012

Teaching method

Main lectures with exposure of the contents of the course. Presentation of cases and problem solving.


The evaluation will be made taking into account the following parameters:

- Exam (100%).

Evaluation method

The evaluation will be made taking into account the following parameters:

- Exam (100%).


Students with a grade equal to or greater than 10 (0 - 20) values. Exist two evaluation periods.  The 2nd evaluation period will only be held if required by the students and by agreement with the conductor.


Subject matter

1. Integration of Carbohydrate, Fat, and Protein Metabolism

2. Cellular Mechanisms Involved in Metabolic Regulation

3. The Nervous System and Metabolism

4. Chronobiology, metabolism and nutrition
Epigenetic regulation

5. Microbiota


Programs where the course is taught: