"Omics" and Personalized Nutrition
Objectives
a) To be able to evaluate on a population and case by case level the potential contribution, in light of available knowledge, of gene-diet interactions in the development of certain diseases;
b) To be able to analyze the benefit / risk balance of dietary recommendations and interventions according to the genotype, microbiota and metabolome;
c) Justify the importance of taking care of diet in the perinatal period for health in adulthood.
d) Apply the foundations of nutrigenomics and personalized nutrition in health promotion.
General characterization
Code
44007
Credits
5.5
Responsible teacher
Professora Doutora Conceição Calhau
Hours
Weekly - Available soon
Total - Available soon
Teaching language
Portuguese
Prerequisites
Bibliography
The presentations available to the students include bibliography used in their preparation.
Teaching method
The teaching methodologies are consistent with the learning objectives. Lectures deliver a complete and detailed exposition of the syllabus. The theoretical-practical classes provide answers to questions and discussions in smaller groups of students of the most important aspects. Additionally, the work done in theoretical-practical classes allow the application of theoretical concepts. The work in groups allow a detailed discussion of the topics presented in small groups and help the teachers to evaluate how the students are learning the topics of the course. The continuous assessment in the theoretical-practical classes, contextualized within the content of the lectures, encourages students to study continuously during the year.
Main lectures with exposure of the contents of the course. Theoretical-practical classes: analysis and discussion of specific topics with practical interest.
Evaluation method
The evaluation will be made taking into account the following parameters:
- Journal Club (100%).
Students with a grade equal to or greater than 10 (0 - 20) values are approved. Exist two evaluation periods. The 2nd evaluation period will only be held if required by the students and by agreement with the conductor.
Subject matter
1. Introduction
Concept of nutrigenetics, nutrigenomics and personalized nutrition.
2. Diet and gene expression
Short-term gene expression regulation
Diet and epigenetics
3. Perinatal programming
Diet in early life and metabolic programming
4. Gene polymorphisms and responses to diet
Diet as a risk or preventive factor of pathologies.
Nutrigenetics of cancer, osteoporosis, cardiovascular disease and obesity
5. Microbiota and Microbial Metabolites
Interaction between genomics, microbiota and metabolomics
6. Workshop case studies
Case studies in personalized nutrition