The main purpose of this course is to raise awareness towards the increasing relevance of nanotechnology, with particular emphasis on nanotechnology in biomedical applications.
In particular, it is intended to stimulate the students’ understanding of concepts and underlying mechanisms of nanotechnology applications in biodiagnostics and construction of biosensors, within a broader field of developments in clinical diagnostics and biomedicine research.
José Ricardo Ramos Franco Tavares, Pedro Miguel Ribeiro Viana Baptista
Weekly - 4
Total - 50
General knowledge of physics, engineering, chemistry, biochemistry and molecular biology
“Nanobiotechnology: Concepts, Applications and Perspectives”
C.M. Niemeyer, C.A. Mirkin (Eds.), 2004, Wiley-VCH, Weinhein, Germany
B.D. Fahlman, 2007, Springer, Dordrecht, the Netherlands
“Bionanotechnology”, D.S. Goodsell, 2004, Wiley-Liss, Hoboken, NJ, USA
Lectures will have a duration 2 h duration and will include problem solving. Each week, the first 2 hours will be taught by the Lecturers, and the second 2 hours will be taught by invited experts or groups of three students will present their Seminars.
Two written tests including all matters taught by the Professors and invited experts (each test corresponds to 25% of the final grade). Alternatively, this evaluation component of 50% can be obtained in an examination after the end of classes (“Recurso”). The seminar presented by the students corresponds to 40% of the final grade and takes into consideration the presentation, the discussion and the documentation submitted. The discussion period after each of the student’s Seminars counts by 10% of the final grade and takes into consideration questions posed by the audience students to their colleagues presenting.
Historic perspective on the origin of Nanotechnology
Scale effect and properties of nanomaterials.
Nanofabrication: bottom-up vs. top-down approach
Microscopy for nanomaterials characterisation (TEM, SEM, SPR)
Bionanotechnology and Bionanomachines
Nanoparticles for clinical applications
Nanotechnology and Green Chemistry
Construction of nanostructures
DNA based nanostructures
Protein based nanostructures
DNA & RNA (cross-linking vs. non-cross-linking)
Nanoparticles for drug delivery and nanovectors for gene therapy.