Organic Chemistry II
Complementary basic formation on Organic Chemistry
Maria Manuela Marques Araújo Pereira
Weekly - 4
Total - 63
Silverstein, R. M.; Bassler, G. C.; Morrill, T. C. "Spetrometric Identification of Organic Compounds" 5th edition, John Wiley and Sons, 1991.
Clayden, J.; Greeves, N.; Warren, S.; Wothers, P. “Organic Chemistry”, Oxford University Press, 2nd Ed., 2012.
Santos, P. P., “Química Orgânica volume I e II”, IST Press, 1ªedição, 2011.
March, J. “Advanced Organic Chemistry”, Wiley Interscience, 6ª Ed., 2007.
Laboratory work, lectures supported by slides and problems in TP classes.
Frequency in the course unit is required and continuous assessment is carried out which involves:
Two tests at FCT - 1/3 of the final grade
TP classes 8 to 12 moments of distance assessment over the 13 weeks (1/3 of the final grade)
moodle tests (multiple choice or other)
Laboratory - 1/3 of the final grade (mandatory equal to or greater than 9.5 values)
Students who have acquired frequency in previous years will see the laboratory component replaced by that registered grade, which in total will have a weight of 1/3 in the final grade. If they do not take the TP component, the final test grade will be 2/3 of the grade. If justified, the test will have a second part corresponding to the TP component.
Conformational analysis. Conformation vs. Configuration. Conformation of linear and cyclic.
saturated and unsaturated compounds .
Nucleophilic substitution reactions on saturated carbon. Nucleophilic aliphatic substitution: SN1 and SN2 mechanisms.
Elimination reactions. Mechanisms E1 and E2. Substitution versus elimination. Mechanism E1cb.
Unsaturated compounds as nucleophiles. Electrophilic addition. Electrophilic addition to conjugated dienes. Cycloaddition. Diels-Alder reaction.
Formation and reactions of enols and enolates. Tautomerism. The aldol reaction.
Reactivity of aromatic compounds. Electrophilic aromatic substitution reactions. Nucleophilic aromatic substitution reactions. Mechanisms of addition-elimination and elimination-addition. Diazonium salts.
The electromagnetic spectrum. Kinds of spectroscopy. 1H-NMR spectroscopy, IR and UV-Vis. Mass spectrometry and elemental analysis. Application examples.