José Ricardo Ramos Franco Tavares
Weekly - 5
Total - 61
Human Drug Metabolism: An Introduction, Michael Coleman, 3rd Edition (2020), Wiley-Blackwell, ISBN: 978-0-470-74217-4 (Principais capítulos abordados: 1 a 5 e Apêndices)
Drug Metabolism in Drug Design and Development, Donglu Zhang, Mingshe Zhu, W. Griffith Humphreys, eds., 1st Edition (2007), John Wiley & Sons, ISBN: 978-0-471-73313-3
Handbook of Chemoinformatics, ed. Johnann Gasteiger, Wiley-VCH, 2003.
Autodock tutorials http://autodock.scripps.edu/faqs-help/tutorial
High-Resolution NMR Techniques in Organic Chemistry Book, Timothy D.W.Claridge, 3rd Edition (2016), Elsevier Science, eBook ISBN: 9780080999937
Theoretical/Practical classes are presentation of the themes by the Professor., intersepersed with analysis and group discussion, in classroom, of scientific articles. Practical classes are learning and practice of computational methods for the analysis of the drug-protein interaction, as well as presentation of group seminars, followed by discussion in classroom.
Theoretical-practical evaluation (40% of the final grade) with two components:
1) 10% - Four best grades of five Quizes on Moodle after each chapter.
2) 30% - Final test about all the theoretical-practical contents of the semester, taught by Prof. Ricardo Franco
The grade in this component must be equal or above 9.5 in order to be accounted for calculating the final grade of this course. However, there is no threshold grade on either Quizes or test. The absence to any of these evaluation parts, gives a grade of zero.
Seminar evaluation (30% of the final grade): For this grade both the quality of the presentation of the Seminar and its PDF version will be taken into account.
Drug Design evaluation (40% of the final grade) with two components:
1) 10% - average of two grades in Quizes on Moodle after each block (Docking and NMR interactions).
2) 20% - Multiple choice final test, about all the contents of the semester on this part.
There is no threshold grade on either Quizes or test. The absence to any of these evaluation parts, gives a grade of zero.
The recourse exam (70% of final grade), can be used by students that had an average classification in the tests below 9,5; or by students that want to improve their final grade (in the latter case, the student must register and pay the due fee). This exam will include only the theoretical-practical part taught by Prof. Ricardo Franco (60% final grade) and the drug design part (40% final grade) evaluations. The drug design evaluation will focus equally on both themes approached during druig design sessions.
Programs where the course is taught: