Emerging Zoonoses Caused by Tremates and Other Helminths
After this unit, students should be able to: 1. Identify the major emerging and reemerging zoonoses and their etiological agents. 2. Associate the main intermediate hosts with their geographical distribution. 3. Know the immunological diagnostic techniques applied to analyze the results and their applicability. 4. Assess the different molecular diagnostic techniques, applied to trematodes and their intermediate hosts. 5. Select the genetic markers most widely used in the study of trematode and its application in different epidemiological studies. 6. Explain the different approaches of the techniques applied in malacological survey during a field work.
Maria Manuela Calado
Weekly - Se a UC for oferecida como opcional, o horário será disponibilizado no 2º semestre
Total - 33,5
• MasComa, S., Valero, A.A., Bargues; M.D., (2009). Climate change effects on trematodiases, with emphasis on zoonotic fascioloasis and schistosomiasis. Veterinary Parasitology, 163: 264280. • Paull, S.H. and Pieter T.J. Johson., (2011). Hight temperatures enhance host pathology in a snailtrematode system: possible consequences of climate change for the emergence of disease. Freshwater Biology, 56: 767778. • Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ and Jacobson J (2008). Helminth infections: the great neglected tropical diseases. J Clin Invest. 118 (4): 1311–1321. • Lustigman S, Prichard RK, Gazzinelli A, Grant WN, Boatin BA, McCarthy JS, Basáñez MG., (2012). A research agenda for helminth diseases of humans: the problem of helminthiases. PLoS Negl Trop Dis, 6 (4):e1582. • Cook C.G., Zumla A.I. (2008). Manson’s Tropical Diseases, 22ª Ed. Elsevier Science, UK E: 1800 pp.
The theory lesson (T); The theoretical and practical lessons (TP); Practice in the laboratory (PL); Seminar (S); Malacological survey in field work (1 day); The Orientation Tutorial (OT): general monitoring and evaluation work for evaluation methodologies.
• Seminar, followed by discussion. Should include review of control strategies and a proposal for a specific situation. • Individual analysis of the critical writing of the paper presented by his group, with about 2000 words (+ 200 words), except graphs and bibliography. Should include analysis methodology and results in the context of existing literature, as well as possible alternative approaches and future. The final grade will be distributed as follows: • Continuous evaluation 10%, • Seminar 40%, • Critical commentary written individual 50%.
I. Trematodes with the importance in human and animal health. The importance of the intermediate hosts insight the climate change. II. The trematodes emerging and reemerging: the causes and effects. III. The immunological diagnostic techniques: concepts and generalities. IV. Different molecular techniques applied to the identification of the parasite in snails, V. Mechanisms of resistance to the various trematodes, resistance markers and drug resistance mechanisms used in therapy. VI. The molecular epidemiology: from theory to practice. Practical application of bioinformatics. VII. Introduction to the techniques applied in malacological survey during a field work.
Programs where the course is taught: