Clinical Pathology and Immunology of Tropical Infectious Diseases


After this unit, students should be able to:
1. Describe the structure of the immune system and immunopathogenesis of infectious processes.
2. Understand microbiological, parasitological and molecular techniques.
3. Be aware of the existing guidelines for collection of biological material and handling of samples and biological specimens.
4. Know the principles of the techniques used in diagnosis lab.
5. Interpret diagnostic tests.
6. Identify the needs of a diagnostic lab for tropical infectious diseases.

General characterization





Responsible teacher

Gabriela Santos-Gomes


Weekly - 7,5

Total - 36

Teaching language

English and Portuguese


Not applicable


• Immunology. (2006). 7th edition. Roitt I., Brostoff J., Male D. (Ed.), Mosby, London, 544 pg.
• The cytokine handbook. (2008). 3rd edition. Thomson A. Academic Press, London, 1017 pg.
• Practical Clinical Pathology 1st Edition. Mais DD. ISBN-13: 978-0891895985
• Artigos científicos de revisão.
• Artigos científicos experimentais.

Teaching method

Tutorial support

Evaluation method

The assessment of learning outcomes will take into account the level of success achieved in the final examination, the performance of the seminars and of spontaneous or induced interventions. Rating equal to or greater than 10 on a 0-20 scale provides the curricular unit approval.

Subject matter

I. Constitution of immune system. Innate and acquired immunity. Lymphocyte differentiation. Humoral response. Regulation of effector response. Immune homeostasis.
II. Immunopathogenesis of infectious diseases.
III. Microbiological, parasitological and molecular methodologies.
IV. Lab diagnosis of tropical infectious diseases. Guidelines for collection and maintenance of biological samples. Use of lab equipment. Flow cytometry. Validation of diagnostic tests.
V. Components of diagnostic lab.


Programs where the course is taught: