The role of Microbiome in Health and Disease
Objectives
- Understanding the relationship of the microbiome with health and disease;
- To know the role of the intestinal microbiota for the physiological balance;
- To know the role of the microbioma in the different infections (genito-urinary, cutaneous, respiratory, rheumatologic);
- Understanding the role of the microbiome in diabetes and transplantation;
General characterization
Code
21000
Credits
6
Responsible teacher
Prof. Doutor Paulo Paixão
Hours
Weekly - Available soon
Total - Available soon
Teaching language
Portuguese
Prerequisites
Bibliography
Andersen SB, Shapiro BJ, Vandenbroucke-Grauls C, de Vos MGJ. Microbial evolutionary medicine: from theory to clinical practice. Lancet Infect Dis. 2019 Apr 30. pii: S1473-3099(19)30045-3. doi: 10.1016/S1473-3099(19)30045-3.
Vázquez-Baeza Y, Callewaert C, Debelius J, Hyde E, Marotz C, Morton JT, Swafford A, Vrbanac A3, Dorrestein PC. Knight R Impacts of the Human Gut Microbiome on Therapeutics. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:253-270. doi: 10.1146/annurev-pharmtox-042017-031849
Noecker C, McNally CP, Eng A, Borenstein E High-resolution characterization of the human microbiome. Transl Res. 2017 Jan;179:7-23. doi: 10.1016/j.trsl.2016.07.012.
Teaching method
Theoretical classes will be taught by the teachers of the course via Zoom, depending on their respective specializations. The form of lecture, in which they will address issues considered essential by providing data to guide students to individual study.
Evaluation method
Student assessment Final written examination with a multiple choice test of 20 questions (duration 30 minutes) 50% (Face-to-face).
Subject matter
- Introduction to the microbiome and its relationship with health and disease;
- The contribution of the microbiome to the physiological balance;
- The importance of the microbiome in some of the major human infections;
- General concepts of real-time PCR and specific application to the study of the microbiome;