Translational and Precision Medicine
Translational Medicine is defined as scientific research that helps speed up the translation of scientific discovery into clinical practice and effective amelioration of human health and wellbeing. Thus, Translational Medicine is responsible for bridging the gap, exploring and converting, from basic research or population studies into clinical application, potentiating the available instruments of diagnosis, monitoring, and treatment of specific pathologies.
Precision medicine is an approach to treat and prevent pathologies that seeks to exploit effectiveness by taking into account individual variability in genes, environment, and lifestyle.
By the end of the course students must have acquired knowledge and competences regarding the entire process associated with Translational and Precise Medicine.
Prof.ª Doutora Helena Soares
Weekly - Available soon
Total - Available soon
* The paradox of precision medicine. Jonathan Kimmelman & Ian Tannock Nature Reviews Clinical Oncologyvolume 15, pages341342 (2018)
* Drug development in the era of precision medicine Sarah A. Dugger, Adam Platt & David B. Goldstein Nature Reviews Drug Discovery volume 17, pages 183196 (2018) * Biomarkers as drug development tools: discovery, validation, qualification and use. Kraus VB. Nat Rev Rheumatol. 2018 Jun;14(6):354-362.
This course is based on swift theoretical introductions, designed to give context regarding the fields of knowledge to be explored, meant to be further detailed by the students themselves through the preparation and discussion.
These group discussions are to be complemented by the students critical analysis of scientific papers in Translational and Precision Medicine.
A multidisciplinary learning is paired with an effective mentoring approach, in which the students will be divided in working groups, with a tutor/group, accompanied by faculty/researcher members who will provide guidance and stimulate discussion. This will facilitate and promote critical thinking of the students Evaluation will include a final project in translational medicine evaluation (50% of the final grade), class participation of the student and the ability to argue (15%), to present and discuss scientific papers (15%), and success in applying acquired knowledge to translational research (20%).
Programs where the course is taught: