Molecular Biomedicine

Objectives

The main objective is to provide students with an overview of the use of molecular technologies in medicine and the relevance of Biomedicine in research.

Specifically, to investigate application of molecular structures in biomedicine: diagnostics and therapeutics; biomedical applications; smart design; nanotechnology for biomedicine.

General characterization

Code

11853

Credits

3.0

Responsible teacher

Maria Alexandra Núncio de Carvalho Ramos Fernandes, Pedro Miguel Ribeiro Viana Baptista

Hours

Weekly - 2

Total - 26

Teaching language

Português

Prerequisites

Available soon

Bibliography

New Advances on Disease Biomarkers and Molecular Targets in Biomedicine; 2013; ISBN-13: 978-1627034555 ISBN-10: 1627034552

Biomedicine; 2012; ISBN 978-953-51-0352-3

Systems Biomedicine: Concepts and Perspetives; 2009; ISBN: 978-0-12-372550-9

Complex Systems Science in Biomedicine; 2006; ISBN: 978-0-387-30241-6; 978-0-387-33532-2

Teaching method

presential classes (or otherwise stated)

Powerpoints and bibliographic references

Evaluation method

Evaluation: (All compulsory for approval grade >9.5)

Quiz (20%) 

Monography (25%) (4 pages)

Presentation/Questions/Discussion of Monography (35%) 

Paper presentation/Questions/discussions (20%) 


Presence in classes are compulsory for
- seminars
- presentations (papers/monography)

Subject matter

  1. Molecular mechanisms in cell control
  2. Molecular actuators
  3. Smart design of molecular structures
  4. Biosensing applications
  5. Molecular therapeutics
  6. Therapeutic nucleic acids: gene silencing and dose compensation
  7. in vitro models
  8. in vivo models
  9. Drug discovery, development and validation
  10. Bionanotechnology and Bionanomachines
  11. Regenerative systems
  12. Translation, ethical and societal impact, regulation.