Pharmacology 1
Objectives
Pharmacology aims to know drugs in their broadest sense: substances of chemical or biological
origin that interfere with physiological and pathophysiological processes.
General characterization
Code
107011
Credits
6
Responsible teacher
Sofia de Azeredo Gaspar Pereira Costa,MARIA TERESA FERREIRA CASTELA ABECASSIS BASTOS LOPES,SUSANA ISABEL MATEUS SANTOS
Hours
Weekly - Available soon
Total - 168
Teaching language
PT
Prerequisites
Available soon
Bibliography
Available soon
Teaching method
General Pharmacology is a one semester course that has a workload of 6 ECTS with 6 contact
hours/week.
Main lectures: Except for the first one (that will be presential, 12 September at 8:00 am, there will
be 2 lessons of 50 minutes, pre-recorded of slides with sound in video mode and made available in
advance in the drive of Pharmacology 1. The link for the drive will be available in the moodle. The
slides in color mode will be also available in leaflet PDF format.
Theoretical-Practical (TP) lessons: 2 Lessons of 2 hour of formative evaluation classes/week in small
groups of students (maximum 16, minimum 10). The main objectives of TP are to stimulate,
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consolidate and monitor individual work during the semester on topics presented in theoretic lesson
and their integration. A summary guide of the TP classes will be available at the drive.
Teaching language is Portuguese, but the slides content and bibliography are preferentially
presented in English.
Evaluation method
Final evaluation includes the distributed evaluation obtained in small groups teaching (TP, 40 %); a
written multiple-choice examination in Portuguese (compulsory, 60 %). The student must have 9.5
values in each of the components and 9.5 in the weighted evaluation. There is also the option of
taking an oral exam. Only students with a classification equal to or greater than 9.5 (out of 20) in the
written test and final weighted classification will be admitted to the oral test. For students who opt
for an oral exam, the grade will be final and will no longer include the weighted grade with the TP
classification. Therefore, in the oral exam, the grade can go up, down or be maintained.
Distributed evaluation in TP will include the attitude of the student and assertiveness in answers
and discussing topics related to theoretic lessons and corresponds to 40% of final grade.
Foreign students included in mobility programs may be admitted to oral examination without
prerequisites in the classification of the written exam or sore in TP lessons, in order to not to penalize
the student for issues related to difficulties of understanding the questions, once the exam is written
in Portuguese.
Subject matter
1. Concepts in Pharmacology
2. Administration routs and drug formulation
3. General principles of pharmacokinetics
4. General principles of pharmacodynamics
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5. Drugs which are proteins
6. Therapeutic drug monitorization
7. General mechanisms of drug toxicity
8. General mechanisms of drug interactions
9. General principles of drug evaluation
10. From origin to therapeutic use: the life cycle of a drug
11. Clinical trials and marketing authorization
12. Generic and biosimilar drugs
13. General Pharmacology of the Renin angiotensin aldosterone system
14. General Pharmacology of adrenergic transmission
15. General Pharmacology of cholinergic transmission
16. General pharmacology of inflammation
17. Anti-inflammatory non-steroids
18. Glucocorticoids
19. General pharmacology of histamine
20. Pharmacology of cellular proliferation
21. Antitumoral dugs
22. Immunosuppressants
23. Pharmacology of the ionic transport
24. Local anaesthetics
25. General anaesthetics
26. Oxygen therapy and fluid therapy
27. Pharmacology of the Respiratory System