Biomaterials
Objectives
To acquire deep knowledge in the area of biomaterials with detailed understanding of the composition and properties of the major classes of biomaterial used in medical devices, manufacture process and applications, interactions with implanted biomaterials, and issues associated with the use of surface modification methods to enhance the biocompatibility of materials. Regulatory and standards associated with quality will be included.
General characterization
Code
5340
Credits
6.0
Responsible teacher
João Paulo Miranda Ribeiro Borges
Hours
Weekly - 4
Total - 70
Teaching language
Português
Prerequisites
Available soon
Bibliography
- Buddy D. Ratner et. al (ed), Biomaterials Science - An introduction to Materials in Medicine, Academic Press, New York, 2020 (4th Ed.)
- Rolando Barbucci (Ed.), Integrated Biomaterials Science, Kluwer Academic Pub., New York, 2002.
- Teacher'''' handouts
- Scientific articles of significant relevance
Teaching method
The lectures will be supported by powerpoint slides. The objectives of each lesson and reading support are explained on the slides.
The practical classes will be conducted in the laboratory, where students perform exploratory experimental activities of the topics covered in the lectures.
Evaluation method
The evaluation shall take into account a theorico-practical component (50 %) and a practical component (50%) distributed by 5 elements of assessment:
- Evaluation of the theorico-practical component will take into account:
- Activities in class (group) (10%);
- 1 final test (individual) (30 %).
- Evaluation of lab activities (in group) will be done by:
- Performance in Lab classes (autonomy, participation) (5%);
- Quiz tests (10%);
- Report (35%);
- Discussion of the report (10%).
Attendance to all lab classes is mandatory for students to be approved in the course. Final grade will be obtained by the weighted average of all the above cited elements.
Subject matter
Lectures
1. Introduction: Economical, Ethic and Social issues in Biomaterials Science
2. Synthetic biomaterials: structure-property relationships
3. Protein-biomaterial interactions
4. Blood-biomaterial interactions.
5. Immune response to biomaterials
6. Wound healing process
Lab classes
L1 - Production and characterization of hydroxyapatite powders
L2 - Synthesis and characterization of magnetite nanoparticles (assessment of the potential for application in the treatment of cancer by magnetic hyperthermia).
L3 - Development of composite systems based on hydrogels by 3D printing.
Programs
Programs where the course is taught: